#HYPER SYNONYM FULL#

Spasms may last several minutes, but occasionally last for hours. Spasms involving the chest and respiratory muscles can be serious, potentially requiring emergency medical treatment with ventilatory support.

#HYPER SYNONYM FULL#

Spasms of abdominal muscles may lead to individuals feeling full faster than normal (early satiety) leading to unintended weight loss. The legs are often involved, which may lead to falls. The spasms may involve the entire body or only a specific region. Muscle spasms are often very painful and usually worsen existing stiffness.

Spasms can be triggered by unexpected or loud noises, minor physical contact, cold environments, stress or situations that cause a heightened emotional response. In addition to muscular rigidity/stiffness, individuals with SPS also develop muscle spasms, which may occur for no apparent reason (spontaneously) or in response to various triggering events (i.e., stimuli). In some individuals, stiffness may progress to involve the arms or face. As stiffness increases, affected individuals may develop a hunched or slouched posture due to outward curving of the upper spine (kyphosis) or an arched back due to inward curving of the lower spine (hyperlordosis). This leads to a slow, stiff manner of walking. As the disease progresses, stiffness of the leg muscles develops, and is often more pronounced on one side than the other (asymmetrical). The shoulders, neck, and hips may also be affected. Early on, stiffness may come and go, but it gradually becomes fixed. Affected individuals may initially experience aching discomfort, stiffness, or pain, especially in the lower back or legs (predominantly classic type). In many cases, SPS begins slowly over several months or a few years. Affected individuals should talk to their physician and medical team about their specific case, associated symptoms and overall prognosis. In some people, symptoms can be stabilized through medication. The symptoms usually develop over a period of months and may remain stable for many years or slowly worsen.

The severity and progression of SPS can vary from one person to another. The characteristic findings associated with SPS are progressive, fluctuating muscular rigidity that occurs along with muscle spasms. Stiff-person syndrome is considered by many researchers to be a spectrum of disease ranging from the involvement of just one area of the body to a widespread, rapidly progressive form that also includes involvement of the brain stem and spinal cord (PERM). In fact, most individuals with the condition are women. Originally described as stiff-man syndrome, the name was changed to reflect that the disorder can affect individuals of any age and of either gender. Stiff-person syndrome has been described in the medical literature under many different, confusing names. Although the exact cause of SPS is unknown, it is believed to be an autoimmune disorder and sometimes occurs along with other autoimmune disorders. If left untreated, SPS can potentially progress to cause difficulty walking and significantly impact a person’s ability to perform routine, daily tasks. The severity and progression of SPS varies from one person to another. In most cases, other neurological signs or symptoms do not occur.

Spasms may occur randomly or be triggered by a variety of different events including a sudden noise or light physical contact. Muscular rigidity often fluctuates (i.e., grows worse and then improves) and usually occurs along with the muscle spasms.

Stiff-person syndrome (SPS) is a rare acquired neurological disorder characterized by progressive muscle stiffness (rigidity) and repeated episodes of painful muscle spasms.

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